Findings
Challenges related to data safety, quality, privacy, and regulatory requirements in smart sensor technologies.
Bias in standard RCTs due to exclusion of participants with language or motor barriers.
Need for ICT systems to detect smooth transitions in cognitive abilities and everyday functions.

Recommendations
Develop ICT-based procedures that capture relevant clinical features validly.
Ensure data fidelity and robustness in ICT systems.
Incorporate user needs into ICT solutions.
Address data safety and privacy concerns.
Develop international policies for access, security, and privacy in ICT solutions.

Regulatory Considerations
Need for international efforts to address gaps in policies around access, security, and privacy.
Current laws do not cover health information on mobile apps or the Internet.
Lack of regulation could undermine the credibility of RWE results.