Findings
Advantages of MCTs: Investigators highlighted remote data capture, access to real-time data for monitoring, and improved data quality as major benefits. They also noted reduced participant burden due to fewer in-person visits and increased participant engagement through real-time data access.
Challenges of MCTs: Increased site burden due to additional time required for technology setup, troubleshooting, and managing high data volumes was a common theme. Participants faced challenges such as technology unfamiliarity, device management, and potential behavior changes from real-time data access.
Support Needs: Investigators emphasized the need for technical support, staff training, and increased budgetary resources to manage devices and train participants. They also highlighted the importance of clear communication about device selection and capabilities from sponsors.

Recommendations
Sponsors should supply comprehensive device training, including hands-on and supplemental materials, and establish systems for ongoing technical support throughout the trial.
Include funds for device management, staff training, and participant support to accommodate the additional demands of MCTs.
Prioritize user-friendly devices to minimize participant burden and improve adherence.
Collaborate with investigators and participants during trial planning to ensure technologies align with study objectives and participant needs.
Focus on in-person, hands-on training to ensure staff and participants are comfortable with the technologies.

Regulatory Considerations
Devices must meet data security and safety requirements to address Institutional Review Board (IRB) concerns.
Provide detailed information about device safety, storage, and capabilities to ensure compliance with regulatory standards.
Clearly communicate data access levels to participants, minimizing risks of data misinterpretation.